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MugiMugi said:
if your scanning and plan to work with the scans, TIFF is your ONLY friend, DO NOT save it as jpeg ABOSLUTLY NEVER, and PNG is not to prefer either, Why? Because all those format you lose quite a lot of important information while you work and edit your scans, TIFF is made for scanning pretty much. PNG and JPG work fine as an end result, but NEVER use them while you work with the pictures! NEVER.
It would be much more helpful to say what information PNG is losing, then to use a lot of caps.

Also don't go complete overkill on to high DPI, most cases on printed books you will hit the max around 300-600 DPI where the rez just become so high that you start to cell the ink cells and at this point is kind of ueless to scan higher, and the quality if the picture kind of get gross by smoting it out to much after here on to. Some books you can scan higher but it depence on the quality of there printing.
Well, you're not seeing "ink cells", you're seeing the screening patterns--and that's what you want to get.

If the screening/dithering/halftoning resolution of the media is at 300 or 600 DPI, then it's probably useful to scan at 600 or 1200 DPI, so the screening patterns are as clear as possible--so they can be removed cleanly with your favorite descreening tool. If the screening is blurry or has a moire pattern, it's probably not going to descreen as cleanly.

Of course, since the actual data being represented by those dots is lower than the resolution you scanned at, descreening is restoring the image to that original data (approximately)--so there's no point in leaving it at that excessively high resolution. If the source is 300 DPI, and you scanned and descreened at 1200, you have something like 300 DPI worth of data, so scale it back down a bit.