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petopeto said:
Photoshop takes about 6x longer for me than other programs. No few percent more compression is worth wasting a minute and a half of my time to save one image. It's completely broken.
I haven't noticed this on my older AMD X2 machine. On that huge image, all of the ones I listed above were taking 4-5 minutes in saving with max compression. The only fast one was PNGOUT with fast settings.

Maybe CS4 finally fixed it, but I wouldn't be surprised if Photoshop was something like 20% slower. *shrug* Granted if you are going for less intense compression, the others will definitely beat out CS4, since CS4 only does max compression.
Try replacing (backup first) the PNG.8bi with the one from CS4 and see if it works any better. (the Plug-ins\File Formats folder) http://www.mediafire.com/?rv4dj2wzymc